CAR-T

Creator

Creator

Seonglae Cho

Created

Created

2021 Sep 24 17:17

Editor

Editor

Seonglae Cho

Edited

Edited

2024 Mar 1 4:1

Refs

Refs

Chimeric Antigen Receptor T-cell

건강한 사람 또는 암 환자의 혈액에서 T 세포를 추출한 뒤 바이러스 벡터를 이용하여 CAR-T를 발현하도록 한 뒤 환자에게 재투여하는 과정

T세포를 유전자 조작해 암세포 공격력을 증가. 암뿐만 아니라 다발성 경화증이라는 자가면역질환의 임상도 하는중

아토피를 비롯해 류머티즘 관절염, 탈모증 등 다양한 질병이 자가면역질환인데, 자가면역질환들을 낫기가 어려운 질병이 많아서 기대중. 비싸긴 하다 몇억대

Disrupting a Single Gene Could Improve CAR T Cell Immunotherapy, New

Learn how disrupting a gene called SUV39H1 could make CAR T cells more powerful.

Disrupting a Single Gene Could Improve CAR T Cell Immunotherapy, New

https://www.mskcc.org/news/disrupting-single-gene-could-improve-car-cell-immunotherapy-according-to-new-study

Disrupting a Single Gene Could Improve CAR T Cell Immunotherapy, New

Medicine's Endgame

The past, present, and future of cell-based therapy

Medicine's Endgame

https://www.notboring.co/p/medicines-endgame

Medicine's Endgame

한림중개의학연구소(강남)

https://research.hallym.or.kr/Kangnam_TransRes/hallymuniv_sub.asp?screen=ptm103

In biology, chimeric antigen receptors (CARs)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor proteins that have been engineered to give T cells the new ability to target a specific antigen. The receptors are chimeric in that they combine both antigen-binding and T cell activating functions into a single receptor.

https://en.wikipedia.org/wiki/CAR_T_cell

Cancer-fighting CAR-T cells could be made inside body with viral injection

Nature - Scientists are devising ways to edit the genomes of immune cells without having to extract them from those being treated.

Cancer-fighting CAR-T cells could be made inside body with viral injection

https://www.nature.com/articles/d41586-023-03969-5?utm_source=tldrnewsletter

Cancer-fighting CAR-T cells could be made inside body with viral injection

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