Seonglae ChoChimeric Antigen Receptor T-cell
The process of extracting T cells from the blood of healthy individuals or cancer patients, using viral vectors to express CAR-T, and then reinfusing them into the patient
T cells are genetically modified to increase their ability to attack cancer cells. Clinical trials are also underway for multiple sclerosis, an autoimmune disease
Many diseases are autoimmune disorders, including atopic dermatitis, rheumatoid arthritis, and alopecia. Since autoimmune diseases are often difficult to cure, there are high expectations. However, it is expensive, costing hundreds of millions of won
Cancer-fighting CAR-T cells could be made inside body with viral injection
Nature - Scientists are devising ways to edit the genomes of immune cells without having to extract them from those being treated.
https://www.nature.com/articles/d41586-023-03969-5?utm_source=tldrnewsletter
Disrupting a Single Gene Could Improve CAR T Cell Immunotherapy, New
Learn how disrupting a gene called SUV39H1 could make CAR T cells more powerful.
https://www.mskcc.org/news/disrupting-single-gene-could-improve-car-cell-immunotherapy-according-to-new-study
Medicine's Endgame
The past, present, and future of cell-based therapy
https://www.notboring.co/p/medicines-endgame
