New CRISPR-based tool inserts large DNA sequences at desired sites in cells
Building on the CRISPR gene-editing system, MIT researchers designed a new tool that can snip out faulty genes and replace them with new ones. The new technique, PASTE, could hold promise for treating diseases that are caused by defective genes with a large number of mutations, such as cystic fibrosis.
https://news.mit.edu/2022/crispr-gene-editing-dna-1124
