Fever is defensive climate change pushing an invader outside its ideal temperature. Most animals increase their core temperature when they are sick. Fish swim into warm waters, lizards bathe in the sun. Bees heat up the air inside their hive.
Pyrogen, “The creators of heat” float and pass right into your brain, where specialized receptors pick them up and crank up your internal thermostat. First you begin to shiver. Your skeletal muscles contract really quickly, which generates a lot of heat in your core. You burn about 10% more calories to stay alive for every degree centigrade you rises. The elevated temperature is harmful not only to antigens but also to the body's own cells. However, it is optimized for the immune system.
If you are sick, you are supposed to feel a reasonable amount of pain so you lie down and save energy. Fever is not a bug but a feature of your immune system. But pain and fever are closely connected and over the counter Painkiller also work against fever. In general it’s fair to say that for temperatures below 40, fever is not dangerous and does not to be treated except pregnant woman, seniors, and seriously weakened patients. Fever over 40 is dangerous to anybody because it is most likely cause by your internal heat monitor fail. There are also evidence that for some diseases like influenza and chickenpox antifever drugs do not help you to heal faster. Also, there are strong indications that more people may survive serious infectious diseases better with a fever. In summary, you decide to feel bad without drugs, you can rest easy in the knowledge that your enemies are having a much worse time than you.
Fever Feels Horrible, but is Actually Awesome!
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Sources & further reading:
https://sites.google.com/view/sources-fever/
Fever feels bad. So we take medication to suppress it – but is this a good idea? It turns out fever is one of the oldest defenses against disease.
What exactly is a fever, and how does it make your immune defense stronger? Should you take a pill to combat it?
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Fever
Fever or pyrexia in humans is a symptom of organism's anti-infection defense mechanism that appears with body temperature exceeding the normal range due to an increase in the body's temperature set point in the hypothalamus. There is no single agreed-upon upper limit for normal temperature: sources use values ranging between 37.2 and 38.3 °C in humans.
https://en.wikipedia.org/wiki/Fever#Pyrogens

Seonglae Cho