Alpha Fold 3

Alphafold 3
Diffusion Model layer added after transformer

https://blog.google/technology/ai/google-deepmind-isomorphic-alphafold-3-ai-model/

AlphaFold 3 predicts the structure and interactions of all of life’s molecules

IsoDDE

It more than doubles the accuracy of protein–ligand structure prediction and achieves a 2.3× performance improvement over AlphaFold 3 on antibody–antigen interactions. Its ability to predict new binding pockets from protein sequence alone, without a

Ligand, is drawing particular attention.

The Isomorphic Labs Drug Design Engine unlocks a new frontier beyond AlphaFold - Isomorphic Labs

Today, we are excited to share an update on our progress towards a new frontier of drug design. We have unlocked a new paradigm of predictive accuracy in understanding our biomolecular world, allowing us to rationally design new medicines on a computer with unprecedented understanding and precision.