Alphafold 3 Diffusion Model layer added after transformer
AlphaFold 3 predicts the structure and interactions of all of life’s molecules
Our new AI model AlphaFold 3 can predict the structure and interactions of all life’s molecules with unprecedented accuracy.
https://blog.google/technology/ai/google-deepmind-isomorphic-alphafold-3-ai-model/

IsoDDE
It more than doubles the accuracy of protein–ligand structure prediction and achieves a 2.3× performance improvement over AlphaFold 3 on antibody–antigen interactions. Its ability to predict new binding pockets from protein sequence alone, without a Ligand, is drawing particular attention.
The Isomorphic Labs Drug Design Engine unlocks a new frontier beyond AlphaFold - Isomorphic Labs
Today, we are excited to share an update on our progress towards a new frontier of drug design. We have unlocked a new paradigm of predictive accuracy in understanding our biomolecular world, allowing us to rationally design new medicines on a computer with unprecedented understanding and precision.
https://www.isomorphiclabs.com/articles/the-isomorphic-labs-drug-design-engine-unlocks-a-new-frontier


Seonglae Cho