Alzheimer's disease Treatment

Creator

Creator

Seonglae Cho

Created

Created

2021 Nov 18 13:41

Editor

Editor

Seonglae Cho

Edited

Edited

2026 Oct 29 8:59

Refs

Refs

Alzheimer's disease Treatments

아두카누 Mab

일라이릴리

솔라네주 Mab

렉세오테라퓨틱스

IBS 연구진이 뇌척수액이 뇌를 감싸는 지주막의 미세한 구멍을 통과해 림프관으로 빠져나가는 경로를 확인한 연구야. 2026년 7월 Cell에 발표. 뇌척수액이 지주막의 미세 구멍 → 뇌막 림프관 → 코 점막의 림프관 → 목 림프절로 이동하는 것을 쥐에서 추적. 사람의 치매를 예방하거나 치료하는 효과까지 입증한 연구는 아니다. 비염 환자는 치매 확률이 높다는 것과 연과. 맞다면 코 많이 파면 치매에 걸릴 확률이 높다고 연관지을수도. 비슷하게 치매가 오면서 냄새를 잘 못 맡기 시작할 수도 있다. 평소에 코호흡을 잘하는 건 도움될 수 있다.

CSF clearance through arachnoid fenestrations to olfactory meningeal lymphatics

Cerebrospinal fluid (CSF) crosses arachnoid fenestrations near the olfactory bulbs to reach dural lymphatics that traverse the cribriform plate, connect to nasal lymphatics, and drain to cervical lymph nodes. Aging impairs this pathway, but intranasal VEGF-C restores the lymphatics and the CSF outflow.

https://doi.org/10.1016/j.cell.2026.06.035

CSF clearance through arachnoid fenestrations to olfactory meningeal lymphatics

https://news.kbs.co.kr/news/pc/view/view.do?ncd=8620502

Alcohol

술 마실 때 ‘이 증상’ 치매 신호라고?…“새해엔 술 줄여야겠네” [생활 속 건강 Talk] - 매일경제

성인 77%가 음주...1회 소주 5~7잔이상 과음은 기억 사라지는 ‘블랙아웃’ 유발 65세미만 치매환자 10%가 알코올 원인 전두엽 손상되면 폭력성도 높아져 해결책은 금주...병원 치료프로그램도 도움

술 마실 때 ‘이 증상’ 치매 신호라고?…“새해엔 술 줄여야겠네” [생활 속 건강 Talk] - 매일경제

https://www.mk.co.kr/news/it/10906613

술 마실 때 ‘이 증상’ 치매 신호라고?…“새해엔 술 줄여야겠네” [생활 속 건강 Talk] - 매일경제

Gene

The world's largest Alzheimer's study has made a gene discovery that could lead to treatments

The study was published on Nov. 21 in the journal Nature Genetics. Researchers from across the globe compared data that involved 32,558 genetic codes from both patients who had Alzheimer's disease, and healthy participants. For the study, 16,036 individuals had Alzheimer's disease and 16,522 individuals did not have AD.

https://interestingengineering.com/health/the-worlds-largest-alzheimers-study-could-lead-to-treatments

The world's largest Alzheimer's study has made a gene discovery that could lead to treatments

Gene Editing

How CRISPR gene editing could help treat Alzheimer’s

Nature - Some researchers hoping that gene-editing technology can conquer forms of Alzheimer’s caused by genetic mutations.

https://www.nature.com/articles/d41586-023-03931-5

How CRISPR gene editing could help treat Alzheimer’s

Ultrasound

Experimental ultrasound treatment targeting brains in trials to help those with Alzheimer's, drug addiction

New experimental treatments using ultrasound energy to target the brain are being tested to help people with Alzheimer's and those battling drug addiction. The pioneering neurosurgeon behind the technology spoke with 60 Minutes.

https://www.cbsnews.com/news/ultrasound-treatment-alzheimers-drug-addiction-patients-60-minutes

Experimental ultrasound treatment targeting brains in trials to help those with Alzheimer's, drug addiction

Spray

One-dose nasal spray clears toxic Alzheimer's proteins to improve memory

One dose of a new treatment, delivered by nasal spray, clears away build-ups of the toxic tau protein associated with Alzheimer’s disease from inside brain cells, improving memory, according to new research. It paves the way for new treatments for the debilitating disease.

https://newatlas.com/health-wellbeing/nasal-spray-tau-proteins-alzheimers/

One-dose nasal spray clears toxic Alzheimer's proteins to improve memory

Mistreatment

Opinion | The Devastating Legacy of Lies in Alzheimer’s Science

Fraud in research needs to end.

https://www.nytimes.com/2025/01/24/opinion/alzheimers-fraud-cure.html

Opinion | The Devastating Legacy of Lies in Alzheimer’s Science

Alzheimer's Is No Longer an Untreatable Disease, Major Report Concludes. Here's Why.

We have more options than you'd think.

https://www.sciencealert.com/alzheimers-is-no-longer-an-untreatable-disease-major-report-concludes-heres-why

Alzheimer's Is No Longer an Untreatable Disease, Major Report Concludes. Here's Why.

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