Drosophila connectome

Creator
Creator
Seonglae ChoSeonglae Cho
Created
Created
2026 Apr 9 15:16
Editor
Edited
Edited
2026 Apr 15 15:7
Refs
Refs

How to simulate via a sensory interface

(a) Retina mapping

  • MuJoCo camera → downsample
  • convert to photoreceptor neuron firing

(b) Olfaction (smell)

  • No real chemical sensing so instead:
    • an "odor scalar field"
    • mapped to activation of a specific neuron group

(c) Touch

  • contact force → mechanosensory neuron firing
  • motor neuron firing → joint torque
Example:
  • a specific neuron cluster → leg movement
Here too:
hard-coded mappings are almost required

4) Calibration / tuning

This is the key trick:
  • synaptic weight scaling
  • global gain tuning
  • noise injection
  • homeostasis constraints

5) (almost certainly) some learning / fitting is involved

A pure copy still won’t run, so:
  • RL fine-tuning
  • parameter fitting
  • or:
    • behavior cloning (partially)
In other words: it’s not reproducing the senses; it’s translating sensory signals into inputs compatible with the sensory neurons.
 
 
 
volume

MANC

 

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