GLP-1

Creator
Creator
Seonglae ChoSeonglae Cho
Created
Created
2025 Jan 28 13:15
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Edited
Edited
2026 Jan 6 0:5
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Refs
GLP-1 medications saw significant improvements across a staggering range of health concerns beyond weight reducing or blood sugar. The patients experienced improvements in addiction and psychotic disorders and the risk of Alzheimer's was decreased.
GLP-1RA drugs act on receptors that are expressed in brain areas involved in impulse control, reward, and addiction, which may potentially explain their effectiveness in curbing appetite and addiction disorders.
 
 
 
 
 

Aging

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Glucagon-like peptide-1
Glucagon-like peptide-1 (GLP-1) is a 30- or 31-amino-acid-long peptide hormone deriving from tissue-specific posttranslational processing of the proglucagon peptide. It is produced and secreted by intestinal enteroendocrine L-cells and certain neurons within the nucleus of the solitary tract in the brainstem upon food consumption. The initial product GLP-1 (1–37) is susceptible to amidation and proteolytic cleavage, which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7–36) amide and GLP-1 (7–37). Active GLP-1 protein secondary structure includes two α-helices from amino acid position 13–20 and 24–35 separated by a linker region.
Glucagon-like peptide-1

Insurance

How GLP-1s Are Breaking Life Insurance
Patients look healthy on paper. Two years later, they're high-risk again.
How GLP-1s Are Breaking Life Insurance
 
 

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