GLP-1 medications saw significant improvements across a staggering range of health concerns beyond weight reducing or blood sugar. The patients experienced improvements in addiction and psychotic disorders and the risk of Alzheimer's was decreased.
GLP-1RA drugs act on receptors that are expressed in brain areas involved in impulse control, reward, and addiction, which may potentially explain their effectiveness in curbing appetite and addiction disorders.
Aging
Ozempic’s New Frontier: The War on Aging
Research suggests potential health benefits beyond what popular diabetes and weight-loss drugs were first approved to treat.
https://www.wsj.com/health/wellness/ozempic-weight-loss-drug-aging-health-benefits-d93a22f8
Huge Study Finds Constellation of Health Benefits for Ozempic Beyond Weight Loss
In a ginormous new study, researchers have begun mapping the manifold health benefits of drugs like Ozempic and Wegovy beyond weight loss.
https://futurism.com/neoscope/glp-1-ozempic-benefits-map

Glucagon-like peptide-1
Glucagon-like peptide-1 (GLP-1) is a 30- or 31-amino-acid-long peptide hormone deriving from tissue-specific posttranslational processing of the proglucagon peptide. It is produced and secreted by intestinal enteroendocrine L-cells and certain neurons within the nucleus of the solitary tract in the brainstem upon food consumption. The initial product GLP-1 (1–37) is susceptible to amidation and proteolytic cleavage, which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7–36) amide and GLP-1 (7–37). Active GLP-1 protein secondary structure includes two α-helices from amino acid position 13–20 and 24–35 separated by a linker region.
https://en.wikipedia.org/wiki/Glucagon-like_peptide-1
GLP-1 is economic earthquake since it affects every type of consumption
The $100 Trillion Disruption: The Unforeseen Economic Earthquake
While Silicon Valley obsesses over AI, a weight-loss drug is quietly becoming the biggest economic disruptor since the internet. Here's why your job, investments, and future depend on understanding it
https://wildfirelabs.substack.com/p/the-100-trillion-disruption-the-unforeseen

Insurance
How GLP-1s Are Breaking Life Insurance
Patients look healthy on paper. Two years later, they're high-risk again.
https://www.glp1digest.com/p/how-glp-1s-are-breaking-life-insurance


Seonglae Cho